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Rare Disease Forum by Genetidoc Genetic Clinic › Forums › Genetic Rare Diseases › Down Syndrome › Is Down syndrome hereditary?
Is Down syndrome hereditary?
Usually not. About 95% of cases occur due to a random error, not something inherited. A small percentage (around 3-4%) result from a “translocation” form, which can be inherited from a parent who carries a balanced translocation, genetic counseling will be helpful in planning for future pregnancies in risk estimation.