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Rare Disease Forum by Genetidoc Genetic Clinic › Forums › Genetics in Pregnancy and Fertility › Prenatal Screening Anomalies › What Is the Retronasal Triangle Marker?
What Is the Retronasal Triangle Marker?
The retronasal triangle (RT) is an ultrasound view of the fetal face taken in the coronal plane, showing three echogenic (bright) structures: the two frontal processes of the maxilla and the nasal bone, forming a triangular shape behind the nose. It is assessed during first-trimester (11–14 week) or early second-trimester scans.
Absence or abnormality of the retronasal triangle is associated with cleft lip/palate and has also been studied as a soft marker for chromosomal abnormalities, since nasal bone and midface development can be affected in conditions like Trisomy 21.
It’s assessed as part of a detailed NT/anomaly scan performed by a trained sonologist – not a routine finding on a basic dating scan.
An absent retronasal triangle typically prompts closer evaluation of the fetal palate and face, and may be factored into overall chromosomal risk alongside other markers.
Limitations:
*Requires a specific imaging plane and operator expertise which not all centers assesses routinely.
*Isolated absence, especially with an otherwise normal detailed scan, has a lower predictive value than when combined with other findings.