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Rare Disease Forum by Genetidoc Genetic Clinic › Forums › Frequently Asked Questions › Why do some genetic conditions affect people so differently?
Why do some genetic conditions affect people so differently, even within the same family?
The same gene change can show up differently between individuals due to factors like other genes present, environmental influences, and natural variation in how the condition expresses itself. This is why two people in the same family with the same gene change can have very different experiences.