*Those diagnosed colorectal or endometrial cancer before age 50.
*Those who had more than one Lynch-related cancer (Cancers in colon, uterine, ovarian, stomach, urinary tract, or small bowel).
*Multiple family members across generations have had cancers related to Lynch Syndrome.
*A close relative was diagnosed with colorectal or endometrial cancer before age 50, even if you yourself have not had cancer.
*A first-degree relative (parent, sibling, or child) has already tested positive for Lynch syndrome.
*Tumour testing findings indicates genetic causes, findings showed microsatellite instability (MSI-H) or abnormal mismatch repair (MMR) protein results on immunohistochemistry — this is often done automatically on colorectal or endometrial tumors and can prompt a referral for genetic testing.
*You have a personal or family history of multiple colon polyps, particularly if diagnosed at a younger age.
*Your family history meets formal clinical criteria used by doctors to flag hereditary cancer risk.