- This topic has 1 reply, 2 voices, and was last updated 5 days, 15 hours ago by .
Viewing 1 reply thread
Viewing 1 reply thread
- You must be logged in to reply to this topic.
Rare Disease Forum by Genetidoc Genetic Clinic › Forums › Genetics in Pregnancy and Fertility › Recurrent Pregnancy Loss › What other factors commonly contribute to recurrent pregnancy loss besides genet
Besides genetics, what other factors commonly contribute to recurrent pregnancy loss?
Recurrent pregnancy loss is often multifactorial. Key contributors include:
*Antiphospholipid syndrome, an autoimmune condition affecting blood clotting, diagnosed through specific antibody blood tests
*Uterine structural abnormalities, such as a uterine septum, fibroids, or scarring, evaluated using ultrasound, hysteroscopy, or magnetic resonance imaging
*Endocrine factors, including uncontrolled thyroid dysfunction, poorly controlled diabetes, and luteal phase issues
*Advanced maternal age, which increases the likelihood of chromosomally abnormal eggs
Lifestyle factors, such as smoking, significant obesity, and heavy alcohol use
It is important to note that in roughly 50% of cases, a definitive cause is not found despite thorough evaluation, which can be difficult for couples to hear but does not rule out a healthy future pregnancy.