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      Anonymous
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      Pregnancy changes how the heart and blood vessels work. Blood volume and the heart’s workload increase, which can place additional strain on the aorta. For someone with Marfan syndrome, this may increase the risk of aortic enlargement or, rarely, a tear. The level of risk varies from person to person and depends partly on the aorta’s size and health. Monitoring may be needed during pregnancy and for several months after delivery.

      Planning should begin before trying to conceive. A cardiologist can review an aortic scan and explain what the findings mean for pregnancy. The person may also meet with an obstetric team experienced in higher-risk pregnancies and a clinical genetics team. Together, they can plan heart monitoring, discuss delivery, and arrange follow-up after birth.

      Medicines need careful review, too. Some medicines used to protect the aorta, including losartan and other angiotensin receptor blockers, can harm a developing baby. Do not stop or change prescribed medicines on your own; ask the care team to review them before pregnancy. If a disease-causing genetic variant is known in the family, a genetics professional can explain available reproductive testing options.

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